| abstract |
The invention relates to a differentiated anuclear cell and a preparation method thereof. The method comprises: culturing conditionally immortalized hematopoietic stem cells in the presence of a reagent that induces differentiation into red blood cells, wherein the reagents are IL-3 and EPO; wherein the reagent induces the differentiation of the conditionally immortalized hematopoietic stem cells into mature red blood cells. The red blood cells can treat a condition selected from the group consisting of: a condition characterized by a defect in mature red blood cells, a condition characterized by blood loss, anemia, Gaucher's disease, hemolysis, neutropenia, thrombocytopenia, Granulocytopenia and hemophilia. |