http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103936628-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10c3f12979e7751f6e54ae5594988766 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 |
| filingDate | 2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dc128b4453568bce7d7381bd9a5c71a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f3d8cee2acaa41321a8d61f3fdf7853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a869e0617700204cec370543e9feee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c11b8ba626e745ce7a3eb17aef3037b4 |
| publicationDate | 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103936628-A |
| titleOfInvention | Intermediate V of anti-hepatitis C drug Boceprevir and its preparation method and application |
| abstract | The invention relates to the technical field of preparation methods for anti-hepatitis C drug Boceprevir. The structural formula of compound V (E) provided by the present invention is as follows. The preparation of this type of compound has the advantages of simple operation and high yield. The compound can be used for the synthesis of the anti-hepatitis C drug Boceprevir, which provides a new idea and method for the synthesis of the anti-hepatitis C drug Boceprevir. Moreover, the ultraviolet chromogenic group in the molecule of this type of compound is more convenient to detect than the original synthesis method. In addition, the introduction of the benzyl group on the hydroxyl group avoids the side reaction caused by the nucleophilicity of the hydroxyl group in the condensation step, which is different from the existing synthetic method. Compared with certain advantages. |
| priorityDate | 2013-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.