http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103933568-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103933568-B |
| titleOfInvention | A kind of water-solubility hypocrellin PLGA nanoparticle and preparation method thereof |
| abstract | The present invention relates to medical art, be specifically related to a kind of water-solubility hypocrellin PLGA nanoparticle and preparation method thereof.Be for carrier with polylactic acid/hydroxy acetate multipolymer (PLGA), PLGA and hypocrellin are dissolved in organic solvent, make oil phase, add in the aqueous phase containing freeze-dried excipient under high-speed stirred, by emulsifying lyophilization, final acquisition carries hypocrellin nanoparticle.According to the biodegradable medical macromolecular materials PLGA that preparation method of the present invention uses American Pharmacopeia (FDA) to ratify, reduce the toxic and side effects that common medicine carrying material brings, improve the water solublity of medicine, the nanoparticle particle diameter obtained is between 20-200nm, make medicine generation red shift, add the absorption at phototherapy window (600-900nm), reduce the dark toxicity of medicine.Raw material is simple, easy to operate. |
| priorityDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.