abstract |
The present invention relates to three new compound formulas I, II, III and stereoisomers or salts thereof for preparing suvorexant, and preparation methods of formulas I, II, III thereof. The present invention also relates to a method for preparing suvorexant. The preparation method obtains chiral compounds I, II, and III through the synthesis of chiral starting materials, which can be used for the synthesis of suvorexant; it has the advantages of simple operation, mild reaction conditions, simple post-treatment, easy purification, high yield, and ee value High, easy industrialization advantages. |