http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103923028-B

Outgoing Links

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04
filingDate 2014-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103923028-B
titleOfInvention Preparation method of valsartan methyl ester
abstract The invention provides a preparation method of valsartan. The preparation method has the technical effects that amide methyl ester and sodium azide are used as raw materials and are catalyzed by amine salt to carry out tetrazole formation reaction; side effects are minimized by controlling the reaction course; main products are furthest generated; unreacted raw materials are recycled and reused; the yield in the preparation method is increased by more than 10% relative to the yields in existing processes; compared with the existing processes, the method has the effect that plenty of high-toxicity wastewater is no longer generated, and is easy to be widely popularized industrially.
priorityDate 2014-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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