http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103911342-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 |
filingDate | 2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103911342-B |
titleOfInvention | A kind of people's giant cell tumor of bone mouse model and construction method thereof |
abstract | The present invention relates to a kind of animal model and construction method thereof, giant cell tumor of bone (GCT) is higher at the sickness rate of China, the most successfully builds people's giant cell tumor of bone animal model.The invention provides a kind of people's giant cell tumor of bone mouse model and construction method thereof, be will to be expelled in the tibia of nude mouse from the primary cell of people's giant cell tumors of bone separation and Culture, the people's giant cell tumor of bone mouse model obtained.Osteolytic characteristic of damage in people's giant cell tumor of bone bone injury mouse model that the present invention is set up is similar to the pathological characters of giant cell tumor of bone clinically, and the cell of survival is the giant cell tumor of bone stromal cell deriving from people.The animal model of the application present invention may be used for the pathogenesis of systematic study giant cell tumor of bone and screens the medicine for the treatment of giant cell tumor of bone further. |
priorityDate | 2013-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.