http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103910740-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103910740-B |
| titleOfInvention | Tetrandrine derivant and preparation method thereof and the application in prepared by antitumor drug |
| abstract | The invention discloses a kind of tetrandrine derivant with anti-tumor activity and preparation method thereof, the general structure of this compound is: The method, with Dibenzylisoquinolinealkaloids compound for raw material, is dissolved in certain solvent, adds reactant Y, mixing, at-20 DEG C～300 DEG C, neutral or under alkali condition, reaction 0.1h～72h, adds acid in reacted solution and is neutralized, then then through separating the prepared purpose product of purification.HepG2 cell lines and human colon cancer cell HT29 are bred by the tetrandrine derivant that the present invention prepares good inhibiting effect, can be used for the preparation of antitumor drug. |
| priorityDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.