http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103910738-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103910738-B |
| titleOfInvention | A kind of Bisbenzylisoquinolincompounds quaternary ammonium salt and preparation method thereof and the application in preparing antitumor drug |
| abstract | The present invention relates to a kind of Bisbenzylisoquinolincompounds quaternary ammonium salt and preparation method thereof and the application in preparing antitumor drug, structure is such as shown in logical formula I, and substituent group is as used in the description.Bisbenzylisoquinolincompounds quaternary ammonium salt of the present invention can be applied in be prepared in antitumor drug, the compounds of this invention has ester based quaternary ammonium salt feature because having Bisbenzylisoquinolincompounds mother nucleus structure simultaneously, at 0.5ug/mL to the human pancreatic cancer cell SW1990 suppression ratio bred higher than 50%, to the suppression ratio of HepG2 cell lines also above 50%, its activity is far above existing tetrandrine compound. <!-- 2 --> |
| priorityDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.