http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103910707-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4433 |
| filingDate | 2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103910707-B |
| titleOfInvention | Containing the sulphonyl hydrazone derivative and its preparation method and application of 8-oxyethyl group-3-nitro-2H-benzopyran structure |
| abstract | The invention belongs to technical field of chemistry, relate to a kind of sulphonyl hydrazone derivative containing 8-oxyethyl group-3-nitro-2<i>H</iGreatT.G reaT.GT-benzopyran structure and its preparation method and application, the general structure of this compound (I) is:n , wherein Rn 1 be independently aryl or the aryl of replacement, the heteroaryl of a 5-10 atom or the substituted heteroaryl of 6-10 carbon atom; Rn 2 independent is H, methyl or ethyl.The present invention is according to medicinal design principle of hybridization, together with the basic pharmacophoric group split of this two class of sulphonyl hydrazone and chromene, synthesize a series of sulphonyl hydrazone derivative containing 8-oxyethyl group-3-nitro-2<i>H</iGreatT.G reaT.GT-benzopyran structure, and antitumor activity has been carried out to them.Experimental result shows compound of the present invention and has good antiproliferative activity.This shows that compound of the present invention can be used for preparing the medicine of Therapeutic cancer. |
| priorityDate | 2014-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.