| abstract |
The object of the present invention is to provide and there is enteron aisle phosphate transporter (NPT-IIb) restraining effect, as the therapeutical agent of hyperphosphatemia and/or the useful compound of the effective constituent of preventive.The thiophene compound represented by following formula (I) has NPT-IIb restraining effect, can use as the agent that prevents and/or treats of hyperphosphatemia.In formula, Rn 1-6 for H or low alkyl group etc., Ln 1-4 for low-grade alkylidene etc., Xn 1 for CHn 2 or O, Xn 2-3 be 0 ~ 1 for CH or N, k are 1 ~ 3, n. |