http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103902849-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-10 |
| filingDate | 2012-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103902849-B |
| titleOfInvention | Based on the method that microarray data and metabolism network determine cancer key metabolic enzymes |
| abstract | The invention belongs to medicine technology field, the method for being related to determine cancer key metabolic enzymes based on microarray data and metabolism network.The inventive method includes setting up gene co-expressing network, divides cancer specific calculating and set up enzyme network, prediction key enzyme and metabolite that coexpression network is module, coexpression network property and module.The inventive method is measurable for enzyme is built in the pass of cancer metabolism, used as the drug candidate target spot for the treatment of of cancer；The cancer key gene of each prediction can be mapped to the metabolite of involved reaction, predict the outcome as the key metabolites of every kind of cancer, and the metabolite also can be used as the drug design basal metabolism thing of candidate；This method can be obviously reduced the scope of experiment search and accelerate target spot finds process, saves time and expense, can be used to screen the drug target of cancer and other complex diseases related to metabolism readjustment, with promotional value. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109628588-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109628588-B |
| priorityDate | 2012-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.