http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103897043-A

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filingDate 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adcfef94a4386838ceba7489c2eb8424
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publicationDate 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103897043-A
titleOfInvention Preparation and application of a membrane-penetrating polypeptide linked to lapatinib
abstract The cell-penetrating peptide of the present invention is composed of 24 amino acids, and is an alternate combination of hydrophilicity and hydrophobicity, and contains a large amount of lysine and arginine. The present invention obtains the desired peptide by solid-phase synthesis. The polypeptide is connected with lapatinib by a chemical synthesis method, and the present invention also provides the effect of the linker passing through the blood-brain barrier and the anti-tumor effect.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108707187-B
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112979754-A
priorityDate 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 32.