http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103897013-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 |
| filingDate | 2014-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103897013-B |
| titleOfInvention | 3 α, 4 alpha-epoxy-16 alpha-bromo-5 5 alpha-androsterone-17-ones and preparation method thereof |
| abstract | The invention discloses a kind of steroidal structure compound 3 α, 4 alpha-epoxy-16 alpha-bromo-5 5 alpha-androsterone-17-ones and preparation method thereof, belong to organic chemistry filed.Prepare 5 αs-androstane-3-alkene-17-ketone and 5 βs-androstane-3-alkene-17-ketone for raw material through zinc powder reduction with androstenedione, after crystallization purifying, obtain individual isomer 5 α-androstane-3-alkene-17-ketone；5 α-androstane-3-alkene-17-ketone reacts with copper bromide, generates 16 α-bromo-5 α-androstane-3-alkene-17-ketone；The mixed solution of the latter and formic acid-hydrogen peroxide reacts, and generates target product 3 α, 4 alpha-epoxy-16 alpha-bromo-5 5 alpha-androsterone-17-ones.Synthesis step of the present invention is few, simple to operate, and economic and practical is strong. |
| priorityDate | 2014-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.