http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103896923-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-454 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2012-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103896923-B |
| titleOfInvention | A kind of Hypoglycemics, its preparation method, comprise its medical composition and its use |
| abstract | The invention provides a kind of hyperglycemia compound and preparation method thereof, pharmaceutical composition and purposes, this compound is the compound shown in formula (I) or its pharmacy acceptable salt, its solvate, its polymorphs body, its enantiomorph or its racemic mixture,?n wherein, Rn 1 , Rn 2 , Rn 3 with Rn 4 be H independently, the optional alkyl replaced, the optional cycloalkyl replaced, the optional alkylthio replaced, the optional alkoxyl group replaced, the optional aryl replaced, the optional aralkyl replaced, or Rn 1 with Rn 2 form the optional cycloalkyl replaced together, or Rn 2 with Rn 3 form the optional heterocyclic radical replaced together, or Rn 3 with Rn 4 form the optional heterocyclic radical replaced together.This compound through the active transport of PepT1 transporter by gastrointestinal absorption, and to be decomposed by enzyme in enteron aisle and in liver and slowly produce BMS-477118, increase the Plasma Concentration of BMS-477118 or extend the BMS-477118 residence time in blood, this stable Plasma Concentration is conducive to increasing hypoglycemic curative effect and reducing side reaction.<!--1--> |
| priorityDate | 2012-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 396.