http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103896782-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-28 |
| filingDate | 2013-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103896782-B |
| titleOfInvention | The method of preparation 2-(N, N-dimethylamino)-2 phenylbutanol |
| abstract | The invention discloses the method that one prepares 2-(N, N-dimethylamino)-2 phenylbutanol.The method comprises the steps: 1) sodium cyanide, dimethylamine, Propiophenone and water are mixed in organic solvent and carries out addition reaction, react complete and obtain 2-(N, N-dimethylamino)-2-phenylbutyronitrile; 2) 2-(N, N-dimethylamino)-2-phenylbutyronitrile is not less than the Water Under solution backflow of 12 in pH value, reacts complete and obtain 2-(N, N-dimethylamino)-2-phenylbutyric acid; 3) 2-(N, N-dimethylamino)-2-phenylbutyric acid and ethanol and the vitriol oil are mixed refuxing esterification, react complete and obtain 2-(N, N-dimethylamino)-2-phenylbutyrate; 4) reduction reaction is carried out in the mixing of 2-(N, N-dimethylamino)-2-phenylbutyrate, reductive agent and water, obtain target product.The method, reaction conditions is gentle, and by product is few, and yield is high. |
| priorityDate | 2012-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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