http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103893200-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_21dec7303572ec6555d93b401eb10aaa |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 2012-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6f251b06840875978667cae82e14929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a1e5733e6fd1d1fbed8434acfa5f0a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5130adba37fcfd81d8ab5087cf47c38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_debe2c7e06cab6ad58da77441830d19c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aecb3cd9d00921cbd634a2b25c3e5f05 |
publicationDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103893200-A |
titleOfInvention | Applications of cordycepin used for preparation of medicines used for preventing and treating atherosclerosis |
abstract | The invention relates to medical novel applications of cordycepin (3'-deoxyadenosine), and more specifically relates to applications of cordycepin used for preparation of medicines used for preventing and treating atherosclerosis and atherosclerosis related diseases. It is confirmed by pharmacodynamic experiments that: cordycepin is capable of inhibiting formation of ApoE-/- mice aorta atherosclerotic plaques significantly, reducing serum TC, TG, and LDL-c contents of animals with hyperlipidemia, increasing total antioxidant capacity and SOD activity of animal serum, reducing MDA content, reducing contents of serum interleukin 2 and interleukin 8 significantly, and inhibiting inflammation. It is confirmed by cell experiments that: cordycepin is capable of inhibiting uptake of mononuclear cell RAW267.4 on cholesterol significantly, and promoting flowing of cholesterol out from cells. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115501245-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107334775-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110464733-A |
priorityDate | 2012-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 419.