http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103893162-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 |
filingDate | 2014-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103893162-B |
titleOfInvention | The application of proadifen in preparation treatment or flu-prevention virus infective medicament |
abstract | The present invention relates to medical art, specifically disclose the application of a kind of proadifen in preparation treatment or flu-prevention virus infective medicament.First the present invention have detected the toxicity of proadifen to mdck cell, and the maximal non-toxic concentration of result display proadifen is 50.0 μMs; Secondly, in the concentration range of totally nontoxic, determine the antiviral activity of proadifen, result shows this micromolecular compound and has significant antiviral activity, and antivirus action is dose-dependent effect; Finally, have detected the antiviral activity of proadifen to the influenza virus of different subtype, result display proadifen can suppress copying of all detected strains of influenza viruses in dose-dependant ground, shows that the anti-influenza virus activity of proadifen has broad spectrum activity.Therefore, it is a kind of New-type wide-spectrum anti-influenza virus medicament that the present invention discloses proadifen first, may be used for the medicine preparing prevention or treatment influenza infection. |
priorityDate | 2014-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 216.