http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103880776-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-135 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-135 |
| filingDate | 2014-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103880776-B |
| titleOfInvention | A kind of method preparing 2-amino-5-alkyl-1,3,4-thiadiazoles |
| abstract | One prepares 2 amino 5 alkyl 1, the method of 3,4 thiadiazoles, step is: add A mol thiosemicarbazides, B mol carboxylic acid, C mol phosphorus oxychloride and D mol silica gel in dry reaction vessel, it is ground to raw material under room temperature react completely, after standing, obtains crude product；Wherein A:B:C=1:(1～1.2): (1～1.2), A:D=1:(5～10)；Adding alkaline solution again in crude product, the pH value to the mixed liquor obtained is 8～8.2, then by mixed liquor sucking filtration, continues sucking filtration with solvent after being dissolved by filter cake, remove silica gel, then the filtrate reduced in volume that will finally give, remove solvent, obtain 2 amino 5 alkyl 1,3,4 thiadiazoles.The present invention is solid state reaction, and with silica gel as carrier, operating process is simple, and the response time is short, and reaction condition is gentle, and equipment requirements is low, and the productivity of target product is up to more than 91%. |
| priorityDate | 2014-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.