http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103865962-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 |
| filingDate | 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103865962-B |
| titleOfInvention | Enzymatic preparation method and application of quercetin-3-O-fatty acid ester |
| abstract | The invention provides an enzymatic preparation method of quercetin-3-O-fatty acid ester. The preparation method comprises the steps of: (1) adding 0.01-0.1mol/L quercetin into an anhydrous organic solvent, and carrying out acylation reaction with an acid anhydride or acyl chloride for 3 to 5 hours to obtain quercetin-3,5,7,3',4'-penta fatty acid ester; (2) adding quercetin-3,5,7,3',4'-penta fatty acid ester to an anhydrous organic solvent, and at 20-80 DEG C, under the catalytic action of lipase Lipozyme IM, performing alcoholysis reaction with n-butanol for 30-100 hours to obtain quercetin-3-O-fatty acid ester. The invention relates to the technical field of medicinal chemistry; the preparation method has the characteristics of mild reaction conditions, high yield, short reaction route, simple process, simple post-processing and easiness for industrial production. The corresponding technical problems in the prior art are solved. |
| priorityDate | 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.