Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-103864793-B |
titleOfInvention |
Substituted purin-9-acetylamino hydroxamic acid histone deacetylases inhibitor and preparation method and application |
abstract |
The invention discloses a kind of substituted purin 9 acetylamino hydroxamic acid histone deacetylases inhibitor and its preparation method and application, compound has such as the structure of formula I.The compound of the present invention has stronger inhibitory activity for HDAC, can prevent or treat the related mammalian disease caused because of histon deacetylase (HDAC) abnormal expression, the invention still further relates to the pharmaceutical applications with the compositions of general formula I compound. |
priorityDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |