http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103860584-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
filingDate | 2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103860584-B |
titleOfInvention | A kind of manufacture method of omeprazole sodium bicarbonate capsule |
abstract | The invention provides a kind of manufacture method of omeprazole sodium bicarbonate capsule, wherein, the amount of the supplementary material unit formulation of omeprazole 40mg dosage form is: omeprazole 40mg, sodium bicarbonate 1100mg, cross-linked carboxymethyl cellulose receive 20-30mg, magnesium stearate 1-5mg; The particle size distribution D of described omeprazolen 10 >=1 μm, D50≤10 μm, Dn 90 ≤ 20 μm; The granularity of described sodium bicarbonate crosses 100 orders.The amount of the supplementary material unit formulation of omeprazole 20mg dosage form is: omeprazole 20mg, sodium bicarbonate 1100mg, cross-linked carboxymethyl cellulose receive 20-30mg, magnesium stearate 1-5mg; The particle size distribution D of described omeprazolen 10 >=1 μm, D50≤10 μm, Dn 90 ≤ 20 μm; The granularity of described sodium bicarbonate crosses 100 orders.The invention has the beneficial effects as follows, by the Task-size Controlling of omeprazole a thinner scope, reduce the unit dose of magnesium stearate, improve the therapeutic effect of medicine; And the raw material hybrid technique simplified in manufacturing process. |
priorityDate | 2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.