| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_870c6e68c09f6b820fc9b7fefe1a56fc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate |
2012-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7262bfd081513e1c81596fbd0765030
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ea14d7bfb7029051a3701a486e31e4b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fd0c726a178331b79d7fdba0f180003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f7b79eb63745fc1765ea8ab6d7b02b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7cccbf8f0cb87d9803db8972bbfc7c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11b0b36e583270d3407579c2de30b79c |
| publicationDate |
2014-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103857788-A |
| titleOfInvention |
Uses of growth and differentiation factor 8 (gdf-8) |
| abstract |
The present invention relates to uses of growth and differentiation factor 8 (GDF-8) in vitro or in vivo for reducing the immunogenicity or risk of rejection of cells such as in particular mesenchymal stem cells (MSC), tissues or materials. The present invention further relates to methods for differentiating MSC in vitro or ex vivo into osteoprogemtors or osteoblastic cells or a cell population comprising osteoprogemtors and/or osteoblastic cells using FGF-2 and GDF-8. In addition, the present invention relates to osteoprogemtors or osteoblastic cells or a cell population comprising osteoprogemtors and/or osteoblastic cells obtainable by such methods and to the osteoprogemtors or osteoblastic cells or a cell population comprising osteoprogemtors and/or osteoblastic cells for use in the treatment of musculoskeletal diseases. |
| priorityDate |
2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |