| abstract |
The invention provides the spiro-compound as hepatitis c inhibitor, pharmaceutical composition and their purposes.Described a kind of compound is the stereoisomer of compound, geometric isomer, tautomer, nitrogen oxides, hydrate, solvate, metabolite, pharmaceutically acceptable salt or prodrug shown in the compound shown in formula (I) or formula (I).In addition, present invention also offers the pharmaceutical composition comprising described compound, described compound and described pharmaceutical composition for suppress HCV to replicate and suppression HCV virus protein function at least one purposes, and described compound and described pharmaceutical composition are for preventing, process, treat or alleviate HCV infection or the purposes of hepatitis C disease of patient. |