http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103833796-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2014-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103833796-B |
| titleOfInvention | Prepare the method for angustose |
| abstract | The invention belongs to the field of chemical synthesis, relate to a kind of method of synthesizing angustose, comprising: 1) utilize Zeo-karb (732 Hn + type) in methyl alcohol to L-rhamnosyl 1-position hydroxyl carry out first glycosides protection obtain compound 2; 2) 2,3-position hydroxyls of compound 2 are carried out isopropylidene protection and obtain compound 3; 3) adopt Swern oxidation system to be ketone carbonyl by the 4-position hydroxyl oxidize of compound 3, obtain compound 4; 4) utilizing the 4-position carbonyl Stereoselective reduction of compound 4 in sodium borohydride or sodium cyanoborohydride is the angustose precursor compound 5 contrary with raw material configuration; 5) by compound 5 at Hn 2 sOn 4 in the aqueous solution, backflow makes it be hydrolyzed and obtains angustose 6.The present invention is with the low L-rhamnosyl be easy to get of valency for starting raw material, and method is easy, practical and efficient. |
| priorityDate | 2014-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.