http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103827316-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103827316-B
titleOfInvention The method for determining DNA mismatch repair function
abstract The present invention relates to be used to determine whether people experimenter has the quantitative approach of the DNA mismatch repair function for damaging;Offer is taken from the diagnosis sample of the people and produces nuclear extract from the sample;Sufficient and MMR the defect nuclear extracts of MMR are provided respectively as positive and negative control;Combine each nuclear extract and at least one Substrate DNA molecule with mispairing;Implement mispairing reparation to determine;And determine whether the sample nuclear extract can repair the Substrate DNA molecule;Wherein described sample includes normal, nonmalignant composition cell, such as fibroblast.The invention further relates to kit, it provides the required reagent for methods described.
priorityDate 2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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