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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F290-00
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filingDate 2014-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103819501-B
titleOfInvention A kind of methylpropenyl phosphoramidite monomer and synthetic method thereof
abstract A kind of methylpropenyl phosphoramidite monomer and synthetic method thereof, relate to hydrogel.The molecular formula of described methylpropenyl phosphoramidite monomer is Cn (38+n1) hn (50+2n1) nn 3 on 6 p, wherein, nn 1 for CHn 2 the number of group, nn 1 =1 ~ 3.First prepare acrylic-OHn 2 , then prepare acylic-DMT, under nitrogen protection finally; after acylic-DMT and N, N-diisopropyl ethyl amine is mixed, dissolve with methylene dichloride; add 2-cyanoethyl N again, be separated with silica gel column chromatography after the reaction of N-di-isopropyl chloro phosphoramidite, obtain methylpropenyl phosphoramidite monomer.Synthesis material is cheap, step simple possible; After synthetic DNA, purification efficiency is higher, and then can obtain higher polymerization efficiency; Any one position of DNA sequence dna can be embedded into as required.
priorityDate 2014-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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