abstract |
The invention discloses a synthetic method of a compound DZCY06 and application of the compound in preparation of drugs for treating diabetes. By means of in vitro rat and mouse islet cell proliferation and PTP1B activity experimental studies, it is found that the compound DZCY06 can promote islet cell proliferation and inhibit PTP1B activity. Meanwhile, the in vivo study shows that the compound DZCY06 can improve the blood sugar level and the insulin level of alloxan hyperglycemic rabbits obviously and has an obvious hypoglycemic effect. |