http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103804469-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-117 |
| filingDate | 2014-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103804469-B |
| titleOfInvention | The preparation method of Ka Feizuo meter intermediate |
| abstract | Present invention is disclosed the preparation method of a kind of Ka Feizuo meter (Carfilzomib) intermediate (α S)-[[2-(4-morpholinyl) acetamido] benzene butyryl]-L-leucyl-L-Phe ester (I), it comprises the steps: with 2-(4-morpholinyl) acetic acid (V), 4-phenyl Gamma Amino Butyric Acid ester (VI), L-Leu ester (VIII) and L-Phe ester (X) are raw material, through there is amidate action and hydrolysis reaction generation (S)-[[2-(4-morpholinyl) acetamido] benzene butyryl]-L-leucyl-L-Phe ester (I).Compared with prior art, this preparation method's concise in technology, raw material be easy to get and side reaction few. |
| priorityDate | 2014-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.