http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103804315-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 |
filingDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103804315-B |
titleOfInvention | A kind of preparation method of 5-An methyl oxazolidinone compounds |
abstract | The invention discloses a kind of preparation method of 5-An methyl oxazolidinone compounds (<b>I</bGreatT.Gr eaT.GT), the method with racemization or optically active 3-halogen-2-hydroxypropyl amino benzenes compounds for starting raw material, with corresponding chloro-formic ester or Boc anhydride reaction under appropriate solvent and alkaline condition, obtain 3-halogen-2-hydroxypropyl-1-anilid compounds (<b>3</bGreatT.Gr eaT.GT), compound L EssT.LTssT.LTb>3</bGreatT.Gre aT.GT alkali or without the need to alkali condition under with ammonia through ammonolysis reaction, obtain racemization or optically active 5-An methyl oxazolidinone compounds (<b>I</bGreatT.Gr eaT.GT),n in formula: Rn 1 represent morpholinyl or 3-oxygen-4-morpholinyl, Rn 2 represent H or F, compound is raceme, <i> (S) </i>-optical isomer or <i> (R) </i>-optical isomer. |
priorityDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.