Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e39a288d149ab88e19e5b980e72fd1e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3e0debe4c7d136042d2f48ad502fb0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e647a218266c582120a9335e730fc27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e723acda14bc9dcc5226044c6af1ee58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56c8e294c874e1dd3c777f100d89fd2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ab2f1bf22e1d159ef02982daa3a9e86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afe6130fc995d72a0c5c7696d26ae782 |
publicationDate |
2015-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-103804303-B |
titleOfInvention |
Epidermal growth factor receptor (EGFR) small-molecule inhibitor pyrimidine derivative as well as preparation method and use thereof |
abstract |
The invention relates to an epidermal growth factor receptor (EGFR) small-molecule inhibitor pyrimidine derivative and a preparation method thereof. The molecular general formula of the EGFR small-molecule inhibitor pyrimidine derivative is as follows: (img file= 'DDA0000476619830000011.TIF' wi= '958' he= '424' /). The EGFR small-molecule inhibitor pyrimidine derivative disclosed by the invention has a significant inhibiting effect on a cancer cell, is cheap, simple and available in used raw materials, fewer in reaction steps, high in yield, and applicable to industrial production, and is a good potential drug. |
priorityDate |
2014-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |