http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103804288-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6aa22684d8e02df8f8ad4fb64d4a16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-85 |
| filingDate | 2012-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_741c24c42ca345ec6f39850d11504efe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_064c9da0c7501940b324c7453cfd1fed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d48f4e83118aa82ebc3725d901f6958 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a944cecfa5ec2fc208f28333c138983d |
| publicationDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103804288-A |
| titleOfInvention | A kind of synthetic method of milrinone |
| abstract | The invention discloses a synthesis method of milrinone, which belongs to the fields of chemical industry and chemical medicine. The method uses 4-picoline as raw material to undergo acetylation reaction with acetic anhydride, the acetylated product is directly condensed with triethyl orthoformate without purification, and the condensed product undergoes ring closure reaction with malononitrile under the condition of absolute ethanol Get milrinone. Its characteristic is that it adopts a method of directly obtaining molecules with complex structures from relatively simple and easy-to-obtain raw materials without separation and purification of intermediates. The milrinone synthesized and prepared by the invention has high yield and high sample purity. Milrinone is an important chemical product, which can be used as a cardiotonic drug, etc. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632025-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111484450-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106243032-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104387320-A |
| priorityDate | 2012-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.