http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103788211-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103788211-B |
| titleOfInvention | Bifunctional peptide, the compound of the bifunctional peptide and nucleic acid molecules formation and the pharmaceutical composition for treating tumour |
| abstract | The present invention relates to a kind of bifunctional peptide, described bifunctional peptide includes cancer cell-apoptosis peptide and cell-penetrating peptide.The invention further relates to a kind of compound formed by the bifunctional peptide and nucleic acid molecules and its purposes in treatment tumour.It is used for the invention further relates to a kind of to antitumor and tumor multi-medicine drug-resistant phenomenon pharmaceutical composition, comprising described bifunctional peptide, oncotherapy gene and chemotherapeutic agent, and its purposes in treatment tumour.Bifunctional peptide involved in the present invention cancer cell specific induction of apoptosis and can promote peptide and its compound to cross over cell membrane.And pharmaceutical composition of the present invention combines bifunctional peptide, oncotherapy gene and chemotherapeutic treatment medicine, the dosage of chemotherapeutics can be not only reduced to significantly reduce its toxic side effect to organism, growth that simultaneously can be preferably to tumour cell suppresses, and effectively antagonizes the multi-drug resistance phenomenon of tumour. |
| priorityDate | 2012-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.