http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103787978-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_edf1d3e1e4d270d8b7beee9af5785b3f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 |
| filingDate | 2012-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5131e30b990f7593dcdda45cd53ec758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1e2f1cff541f7557433e465404281b2 |
| publicationDate | 2014-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103787978-A |
| titleOfInvention | Synthesis method of 1-methylindazole-3-formic acid |
| abstract | The invention relates to a synthesis method of a key intermediate 1-methylindazole-3-formic acid of an anti-vomit medicine granisetron. The method comprises the following steps: reacting a raw material 2'-hydroxyacetophenone with hydrazine hydrate in ethanol, cyclizing under acidic conditions, oxidizing by potassium permanganate, and carrying out N-methylation to obtain 1-methylindazole-3-formic acid. The method has the advantages of easily available raw material, simple route, mild reaction conditions, simple post-treatment, and suitableness for the industrialized large-scale production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110128347-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020253533-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109796410-A |
| priorityDate | 2012-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.