http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103784410-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 |
| filingDate | 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103784410-B |
| titleOfInvention | A kind of Banlangen Polysaccharide MPEG-PLA method for preparing polymer micro |
| abstract | The invention discloses a kind of Banlangen Polysaccharide MPEG-PLA method for preparing polymer micro, multi-emulsion method is adopted to prepare Banlangen Polysaccharide MPEG-PLA block copolymer microsphere, concrete steps are: joined by polysaccharide solution in the oil phase of MPEG-PLA dichloromethane solution, obtain milky colostric fluid under high velocity agitation, colostric fluid is joined in PVA aqueous solution, high-speed stirred 2--5min, subsequently double emulsion is placed on magnetic stirring apparatus and stirs until organic solvent is evaporated completely with the speed of 50--200rpm, finally, by remaining milky white liquid with the centrifugation 15min of 3000--5000rpm, abandon supernatant, get precipitation, precipitation is after tri-distilled water cyclic washing 3 times, namely lyophilization obtains Banlangen Polysaccharide MPEG-PLA microsphere.The medicine carrying microballoons electron-microscope scanning result profile that the method obtains is round and smooth, even particle size, mean diameter 874.3nm, and the coefficient of dispersion is 0.749, and envelop rate is up to 86%, and release rate is up to 79.1%, and release time is longer, is 26 days, and slow release is mild, and dashing forward, it is lower to release rate. |
| priorityDate | 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.