http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103784407-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103784407-B |
| titleOfInvention | Graphene oxide-loaded adriamycin nano-particles of a kind of folate-mediated PEG-and preparation method thereof |
| abstract | The present invention relates to graphene oxide-loaded adriamycin nano-particles of a kind of folate-mediated PEG-and preparation method thereof.The present invention carries out functional modification with folic acid and PEG to it, final load model drug amycin is prepared from, invention increases the drug loading of nanoparticle, improve target-oriented drug, significant prolongation plasma half-life and mean residence time, and then improve doxorubicin effect, the present invention can reduce the toxic and side effects of amycin, prolong drug holdup time and improve the targeting of medicine, thus strengthen its antitumor curative effect.The present invention is wide for some Antitumor test, but side effect is serious, and the medicine that toxicity is large has important clinical meaning. |
| priorityDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.