http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103772494-B

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publicationDate 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103772494-B
titleOfInvention Antibacterial peptide secreted by clostridium butyricum as well as preparation method and application thereof
abstract The invention discloses an antibacterial peptide secreted by clostridium butyricum as well as an amino acid sequence and an application thereof. The amino acid sequence of the antibacterial peptide is represented by a sequence table SEQ ID NO:1, the molecular weight is 2264.6 Daltons and the isoelectric point is 8.64. A preparation method comprises the following steps: carrying out cation exchange, molecular sieve chromatography and reverse high performance liquid chromatography on the antibacterial peptide secreted by the clostridium butyricum in an ammonium sulfate precipitation culture medium to purify the antibacterial peptide. The antibacterial peptide has obvious antibacterial activity, does not have hemolysis effect on erythrocytes of pigs and can be used for developing and preparing an antibacterial medicine.
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