http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103772346-B
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a648918bae4ac0de578431f5bd46ff6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-68 |
filingDate | 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d20df7dfbe96318e254cae5e34b70882 |
publicationDate | 2015-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103772346-B |
titleOfInvention | Bicyclol prodrug compound, and preparation method, pharmaceutical composition and application thereof |
abstract | The invention discloses a bicyclol prodrug compound, and a preparation method, a pharmaceutical composition and application thereof. The structure of the bicyclol prodrug compound or the medicinal salt of the bicyclol prodrug compound is shown in the formula (I), wherein R represents hydrogen, C1-C6 alkyl, C3-C8 naphthenic base, alkali metal ion, alkaline-earth metal ion, ammonium salt, and heteroatom or heterocycle-substituted C1-C6 alkyl or C3-C8 naphthenic base. According to the bicyclol prodrug compound, a hydrophilic fragment is introduced on the basis of bicyclol to generate active pharmaceutical bicyclol in vivo through metabolism, thereby treating or preventing viral hepatitis and liver injury caused by chemicals or medicines. |
priorityDate | 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.