http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103772188-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-42 |
| filingDate | 2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103772188-B |
| titleOfInvention | The preparation method of R-(+)-α-Cyclo hexyl mandelic acid |
| abstract | The invention discloses a kind of R-(+) preparation method of-α-Cyclo hexyl mandelic acid, belong to organic chemistry filed, specifically comprise: S1. reacts: add acetonitrile, water, α-Cyclo hexyl mandelic acid, TYR methyl esters in reactor, to lower the temperature after reaction filtration, solid is for reclaiming TYR methyl esters and S-(+)-α-Cyclo hexyl mandelic acid, filtrate is for subsequent use; S2. be separated: filtrate reduced in volume obtains oily matter, adds toluene and water, stratification in oily matter, organic phase is used for next-step operation; S3. crystallization: comprise a crystallization and secondary crystallization; S4. dry: by a crystallization and secondary crystallization gained R-(+)-α-Cyclo hexyl mandelic acid is dry under the condition of temperature≤50 DEG C, obtained dry product R-(+)-α-Cyclo hexyl mandelic acid.R-(+ provided by the invention) preparation method of-α-Cyclo hexyl mandelic acid have simple to operate, production cost is low, the advantage that yield is high, energy consumption is little, products obtained therefrom optical purity is high. |
| priorityDate | 2014-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.