abstract |
The present invention relates to trifluoromethyl-oxadiazole derivative of new formula (I) and pharmaceutically useful salt thereof, in formula (I), all variablees all as in specification sheets define, the invention still further relates to its medicinal compositions, its pharmaceutical compositions product and the purposes as medicine thereof, particularly by suppressing HDAC4 to be used for the treatment of nerve degenerative diseases, amyotrophy or metabolism syndrome. |