| abstract |
The invention relates to a tumstatin No.30 peptide having anti-tumor effect, and a preparation method and an application thereof. The amino acid sequence of the tumstatin No.30 peptide is SEQ No.1, and a nucleotide sequence for coding the tumstatin No.30 peptide is SEQ No.2. The tumstatin No.30 peptide is characterized in that nonactive fragments in the No.19 peptide are deleted while the anti-tumor activity of the tumstatin No.41 peptide is maintained, the number of amido acids of the fusion peptide is reduced so that the production cost of the fusion peptide, especially the production of chemical synthesis, is reduced, and furthermore, the safety of drug use is improved. |