http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103755709-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2014-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103755709-B |
| titleOfInvention | The microwave assistant preparation method of sildenafil derivative |
| abstract | The invention discloses a kind of microwave assisted synthesizing method of sildenafil derivative, the method is mainly taking 2-alkoxybenzoic acid and 4-amino-1-methyl-3-n-pro-pyl-1H-pyrazoles-5-formamide as initiation material, through amidatioon, cyclization, mono-nitration, nitroreduction, the reaction such as guanidinated, prepare sildenafil derivative. The inventive method has greatly shortened the time of reaction, has improved the efficiency of reaction, and productive rate is high, and purity is good; Easy and simple to handle, be easy to control; Be conducive to the suitability for industrialized production of silaenafil analog. |
| priorityDate | 2014-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.