http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103755624-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-255 |
| filingDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103755624-B |
| titleOfInvention | A kind of synthetic method of piperidine derivative |
| abstract | The invention discloses a synthesis method of piperidine derivatives. Described piperidine derivative is the tartrate of structural formula (I): Wherein, R 1 is an amino protecting group, R 2 is a phenyl group or an alkyl-substituted phenyl group, and R 3 is a C1-C6 alkyl group; the piperidine derivative is composed of a compound of structural formula (II) and L- tartaric acid reaction, and then obtained by separation, After introducing the S-type substituent group on the amino group at the 3-position of the piperidine ring, it can obviously improve the Split out of Effect. The method can be used in the synthesis of the drug Tofacitinib, so as to improve the yield of the drug Tofacitinib. |
| priorityDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.