http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103755621-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 |
| filingDate | 2014-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103755621-B |
| titleOfInvention | The method of polysubstituted indoles is prepared by aryl hydrazines and alkynes |
| abstract | The invention discloses a kind of method preparing polysubstituted indoles.The method, comprises the steps: alkynes cyclization alkynes, catalyzer, alkali and additive shown in aryl hydrazine hydrochloride shown in formula II, formula III carried out in solvent based on carbon-hydrogen bond activation, reacts complete and obtain compound shown in described formula I.The method uses the raw material be easy to get to carry out one pot reaction, and orientating group is in-situ preparation in the reaction, without the need to being preset on substrate.After cyclization, orientating group removes automatically, the NH indoles obtained conveniently carries out further derivatize and obtains the indoles of N-replacement, good compatibility is all had to multiple substituting group, reaction is without the need to additional oxidizer, reaction is without the need to strong acid and strong base, Atom economy is also higher, although the catalyzer used is not cheap, required add-on is little. |
| priorityDate | 2014-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.