http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103751845-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ef17daddab0e2d7329d9b309c82b0b5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02 |
| filingDate | 2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6196844d339096410ace0a02d653044c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d1678cef976fc9bdbf433516bcf0ea8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_073ea73be904cf2bf56c1fe89394748b |
| publicationDate | 2015-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103751845-B |
| titleOfInvention | Tissue engineering biological material for transplanting and restoring peripheral nerve defect |
| abstract | The invention discloses a tissue engineering biological material for transplanting and restoring a peripheral nerve defect. The tissue engineering biological material is prepared through the following steps: firstly, preparing an acellular nerve allograft scaffold by using a chemical extraction method; then culturing an adipose derived stem cell by using fatty tissues collected by a target receptor in an early debridement; finally carrying out induction in vitro by using an exogenous schwann cell endogenus neurotrophic factor to construct a tissue engineered peripheral nerve for later use. The acellular nerve allograft scaffold subject to chemical extraction has no immunogenicity and has a network structure most similar to an organism nerve and excellent biocompatibility, and meanwhile, a stem cell is controllably induced in vitro by using the schwann cell endogenus neurotrophic factor and is differentiated into schwann-liked cells in combination with an ideal scaffold and then transplanted in vivo to become effectiveness. |
| priorityDate | 2014-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.