http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103741467-B
Outgoing Links
Predicate | Object |
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classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M101-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M101-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M13-328 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M13-188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M15-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F8-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D06M13-123 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01F8-10 |
filingDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103741467-B |
titleOfInvention | Be applied to the preparation method that target catches the hyaluronic acid functionalized nano-fiber of cancer cell |
abstract | The present invention relates to and be a kind ofly applied to the preparation method that target catches the hyaluronic acid functionalized nano-fiber of cancer cell, comprise: (1) take water as solvent configuration PVA/PEI spinning solution, then electrostatic spinning is carried out, after drying in containing the drier of glutaraldehyde solution vacuum crosslinking Treatment, obtain the PVA/PEI nanofiber that water stability is good; (2) hyaluronic acid activated is joined in the good PVA/PEI nanofiber of water stability, shaking table is obtained by reacting the Static Spinning PVA/PEI nanofiber of hyaluronic acid functional modification; Add triethylamine again and the amino of PEI/PVA nano fibrous membrane surface residual is all carried out acetylation process by acetic anhydride, finally wash, dry.Low in raw material price of the present invention, preparation technology are simple, and the hyaluronic acid functionalization electrostatic spinning nano fiber of preparation has good pattern and structural stability, biocompatibility and blood compatibility, has a extensive future. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105327357-B |
priorityDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.