http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103724253-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-44 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 |
filingDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103724253-B |
titleOfInvention | A kind of preparation method of Mitiglinide Calcium |
abstract | The invention provides the new preparation process of a kind of Mitiglinide Calcium, the method includes: with cis-hexahydro iso-indoles for raw material, through acylation reaction, alkylation reaction, hydrolysis and salt-forming reaction, prepares Mitiglinide Calcium. Described alkylation reaction and hydrolysis adopt the method for " cooking all things in one pot " to complete, and product purity reaches more than 99.8%, yield more than 36%. Preparation method of the present invention has raw material and is easy to get, and reaction condition is gentle, and operation is simple, and yield is higher, has higher industrial productive value, has realized industrialization at present. |
priorityDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.