http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103720684-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 |
filingDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103720684-B |
titleOfInvention | The application of bentrl hydrothloride in preparation treatment or flu-prevention virus infective medicament |
abstract | The invention discloses the application of bentrl hydrothloride (Dicyclomine Hydrochloride) in preparation prevention or treatment influenza infection medicine.First have detected the toxicity of bentrl hydrothloride to mdck cell, the maximal non-toxic concentration of result display bentrl hydrothloride is 50.0 μMs.Secondly, in the concentration range of totally nontoxic, determine the antiviral activity of bentrl hydrothloride, result shows this micromolecular compound and has significant antiviral activity, and antivirus action is dose-dependent effect.Finally, have detected the antiviral activity of bentrl hydrothloride to the influenza virus of different shaped and hypotype, result display bentrl hydrothloride can suppress copying of all detected strains of influenza viruses in dose-dependant ground, shows that the anti-influenza virus activity of bentrl hydrothloride has broad spectrum activity.Therefore, the present invention discloses bentrl hydrothloride is a kind of New-type wide-spectrum anti-influenza virus medicament, may be used for the medicine preparing prevention or treatment influenza infection. |
priorityDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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