http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103720674-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
| filingDate | 2014-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103720674-B |
| titleOfInvention | Famotidine floating-adhesive micro-tablet capsule and preparation method thereof |
| abstract | The invention discloses a kind of Famotidine floating-adhesive micro-tablet capsule and preparation method thereof, belong to medical art.Said preparation composition comprises famotidine, HPMC K4M, CARBOPOL 971, sodium bicarbonate, microcrystalline Cellulose and magnesium stearate.Famotidine floating-adhesive micro-tablet prepared by the present invention belongs to outside round convex type, and diameter is 3mm, can load in empty hard capsule.Famotidine floating-adhesive micro-tablet of the present invention can realize playing drift in 1min in simulated gastric fluid, and the lasting flotation time reaches more than 8h, and has certain adhesion.Is famotidine microplate prepared by the present invention at 0.1M? in HCl solution, the burst size of 1h is less than 50% of labelled amount.This preparation extends the holdup time of famotidine at gastric, thus reaches the object reducing medicining times, increase curative effect, and the exploitation for famotidine sustained-release preparation provides a kind of alternative dosage form newly. |
| priorityDate | 2014-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.