| abstract |
The present invention relates to antagonist antibodies or fragments thereof that bind human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40, comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO:1, and/or a heavy chain comprising the amino acid sequence of SEQ ID NO:2 CDR2, and/or heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO:3; and/or light chain CDR1 comprising the amino acid sequence of SEQ ID NO:4, and/or comprising the amino acid sequence of SEQ ID NO:5 Light chain CDR2, and/or light chain CDR3 comprising the amino acid sequence of SEQ ID NO:6. |