http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103710308-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15 |
| filingDate | 2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103710308-B |
| titleOfInvention | Muramyl dipeptide is utilized to induce the method for DC-CIK |
| abstract | The invention provides a kind of method utilizing muramyl dipeptide to induce DC-CIK, namely in CIK or DC-CIK nutrient solution, add muramyl dipeptide induction CIK or DC-CIK cell proliferation and differentiation, kill tumor activity with what promote CIK or DC-CIK cell, it comprises the following steps: peripheral blood collection, tumour antigen obtain, mononuclearcell is separated, collect mononuclearcell, the washing of mononuclearcell, the induction of MDP-DC-CIK cell, cultivation.The MDP-DC-CIK cell of present method inducing culture, detects through FCM analysis instrument and finds that the ratio without the restrictive NKT cell of MHC of its CD3+CD56+ is up to can up to more than 80%; Meanwhile, the activity of its killing tumor cell is much higher than the DC-CIK cell of conventional inducing culture, kills knurl percentage laboratory detection result and reaches more than 99%. |
| priorityDate | 2013-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.